Orthotopic and heterotopic ovarian tissue transplantation

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Orthotopic and heterotopic ovarian tissue transplantation

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Heterotopic ovarian transplantation results in less apoptosis than orthotopic transplantation in a minipig model

BACKGROUND Ovarian autotransplantation has shown increasing promise as a clinical method for the preservation of fertility and hormonal function. However, information regarding the success rate of this type of transplantation is limited. We hypothesized that results vary according to the site of the ovarian transplantation. To test this hypothesis, fresh or cryopreserved ovarian strips were aut...

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Embryo development after heterotopic transplantation of cryopreserved ovarian tissue.

BACKGROUND Cancer treatments, including chemotherapy, radiotherapy, and radical surgery, can induce premature menopause and infertility in hundreds of thousands of women of reproductive age every year. One of the ways to possibly preserve fertility before these treatments is to cryopreserve ovarian tissue for later transplantation. We aimed to restore fertility by cryopreservation and transplan...

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Ovarian function and spontaneous pregnancy after combined heterotopic and orthotopic cryopreserved ovarian tissue transplantation in a patient previously treated with bone marrow transplantation: case report.

Cryopreservation of ovarian tissue has been proposed for storing gametes of young patients at high risk of premature ovarian failure. Autotransplantation has recently provided some promising results and is still the unique option to restore ovarian function from cryopreserved ovarian tissue in humans. In this article, we analyse data from the combined orthotopic and heterotopic transplantation ...

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ژورنال

عنوان ژورنال: Human Reproduction Update

سال: 2009

ISSN: 1355-4786,1460-2369

DOI: 10.1093/humupd/dmp021